Le Mars struggled to settle into the game and was down 20-15 after the first quarter.
The 'Dogs outscored the Braves 21-18 but still found themselves down at halftime, 38-36.
Cherokee senior Eric Wilkie scored 23 points of his team's 38 points in the first half.
After the break, Le Mars came out of the locker room with more passion and determination and took charge of the game.
They held the Braves to six points while scoring 15 themselves, taking a 51-44 lead into the final eight minutes.
"Once we got our defense going we were able to get our easy hoops and spread things out a little bit," Irwin said.
The 'Dogs continued to dominate both of ends of the floor in the game's closing stages and outscored their opponent 19-7, resulting in the final score.
"In the second half we came out and played much better, much harder. We played a little more physical," Irwin said. "It was a complete team effort. We did a nice job in a lot of different areas."
One of the key factors in Le Mars' victory was holding Cherokee's Wilkie to just three points after halftime.
"Gabe Rahn did a great job on him in the second half," Irwin said.
Jake Irwin scored a team-high 13 points for the Bulldogs, followed by Kyle Dolph with 11. Tanner Anthony, Parker Rolfes and Tyler Borchers each had ten points. Rolfes had eight assists.
Defensively, Rolfes led his team with eight rebounds and five steals.
"He kept us in the game in the first half," Irwin said about the senior. "He played a nice first half on both ends. He was one of the few that I thought really asserted themselves defensively."
With the win, Le Mars has an overall record of 12-4. They will face Estherville (7-11) in a home game on Friday.
"These are the games that they really look forward to," Irwin said about his team's upcoming opponent. "It's a great opportunity for them to beat one of the better teams in the Lakes Conference. We have got to understand that, come out and play the way we are capable of playing for four quarters."