Both teams were evenly matched in the opening quarter, resulting in a 12-12 tie after the first eight minutes of playing time.
The picture changed in the second stanza when the Lady Panthers picked up the pace and started pulling away.
"In the second quarter is where it got away from us," Lady Rockets coach Mike West said. "At halftime we were down by seven, which I thought we could come back from. But we just couldn't close the gap on them."
The Lady Panthers got off to a good start in the second half and extended their lead to 12 points at one point.
R-U tried their best to get back into the game and managed to get back within reach, with a score of 39-32 after three periods.
But K-P remained strong on defense and got valuable turnovers.
"We rebounded quite well tonight," Lady Rockets coach Nicole Goodwin said. "Best we've boxed out all season."
R-U coach West saw his team's turnovers as one of the keys to their defeat.
"We didn't take care of the ball very well. Too many turnovers," he said.
For Kingsley-Pierson, it was the first victory after two consecutive losses.
Goodwin was pleased pleased with her team's effort.
"We get so many girls in and everybody is going hard. We haven't had a complete game the last few games. It was nice to complete a game, to play solid in all four quarters. Great teamwork tonight," she said.
K-P freshman Marina Keck scored a game-high 17 points.
On the defensive end, freshman Rachel Mercer led her team with eight rebounds. Keck, senior Keely Collins, and freshman Kiana Phelps all had seven. Junior Amanda Weber had five assists and four steals.
The Lady Panthers had several players contributing big off the bench.
"The nice thing about having a deep bench is that if that somebody has an off night somebody can come in and back you up a little bit. Great teamwork tonight - offensively and defensively," Goodwin said.
Senior Brittany Sudtelgte had 16 points and nine rebounds for Remsen-Union. Senior Kelsey Ruden had nine points and 14 rebounds.
The Lady Rockets (5-10) will face Hinton in an away game today (Friday).
"Hinton is going to press," West said. "We're going to have to try to keep our composure and cut down on turnovers."
K-P (10-6) travels to Mondamin today to face West Harrison in their final conference matchup.